RNA-Mediated Gene Silencing in Hematopoietic Cells

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RNA-Mediated Gene Silencing in Hematopoietic Cells

In the past few years, the discovery of RNA-mediated gene silencing mechanisms, like RNA interference (RNAi), has revolutionized our understanding of eukaryotic gene expression. These mechanisms are activated by double-stranded RNA (dsRNA) and mediate gene silencing either by inducing the sequence-specific degradation of complementary mRNA or by inhibiting mRNA translation. RNAi now provides a ...

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ژورنال

عنوان ژورنال: Journal of Biomedicine and Biotechnology

سال: 2006

ISSN: 1110-7243,1110-7251

DOI: 10.1155/jbb/2006/87340